Topical Minoxidil Alone or in combination with Finastride,
Minoxidil or Aminexil for Topical Application

Topical Minoxidil is the only drug approved by USFDA for  hair fall treatment.
A review of literature was done of Minoxidil alone vs Minoxidil in combination with Finastride/Aminexil/tretinoin .
Minoxidil with Finastride did showed some subjective benefit of Increase in thickness on photography.But Not much difference in Hair count.
Minoxidil with Tretinoin didn’t showed any difference with Minoxidil alone.
Aminexil is a new molecule which decreases peri follicular fibrosis. Independent study done by cosmetic company shows it’s effective for Hair fall Treatment .
There is no study of the combination .
To conclude : these combinations are not approved by USFDA.there is no convincing literature to show there superiority over Minoxidil alone.
These products may be helping in some or the other way for hair growth.But hair fall happens due to Multiple reasons.These products may be just USP/extra Amateraium for the Pharmacy company.
May be more studies in future may give clear opinion regarding benefit of these combinations.

This paper was presented in Annual conference of Hair Restoration Surgeons of  India by Dr Sumit Agrawal.

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